Rapamycin for Healthy Aging: Results from the TRIAD Canine Longevity Trial
Randomized, placebo-controlled trial in 586 companion dogs demonstrates modest but significant improvement in cardiac function parameters.
03
Jun
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28
May
NAD+ Decline Reversal in Aged Mice: A Critical Re-evaluation of Recent Claims
Editorial analysis examining reproducibility concerns in high-profile NAD+ precursor supplementation studies.
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15
May
First Phase 2 Senolytic Trial in Diabetic Kidney Disease: Interim Analysis
Interim results from the CLEARANCE trial evaluating dasatinib + quercetin in participants with diabetic nephropathy.
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02
May
Dose-Response Relationship Between Exercise Volume and Leukocyte Telomere Length
Large cohort analysis (n=8,400) reveals a non-linear dose-response curve with diminishing returns above 150 min/week.
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18
Apr
TAME Trial Design Update: Targeting Aging with Metformin
Updated protocol and power analysis for the first large-scale geroprotective trial using an FDA-approved drug.
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05
Apr
Alternative Lengthening of Telomeres (ALT) in Inflammation-Driven Cancers
Mechanistic review of ALT pathway activation in tumor microenvironments with high inflammatory signaling.
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